Abubuwan haɓaka sune sinadarai na wucin gadi (wanda mutum ya yi) waɗanda ke ƙarfafa sel don rarraba da haɓaka. Akwai abubuwa da yawa na girma daban-daban waɗanda ke shafar nau'ikan sel daban-daban. Jikin ku yana yin abubuwan haɓaka ta halitta.
Menene abubuwan girma?
Granulocyte-colony stimulating factor (G-CSF) ana samar da shi a cikin jiki ta hanyar tsarin rigakafi kuma yana ƙarfafa samuwar nau'in farin jini guda ɗaya, neutrophil. Neutrophils suna shiga cikin halayen kumburi kuma suna da alhakin ganowa da lalata ƙwayoyin cuta, ƙwayoyin cuta, da wasu fungi masu cutarwa.
Hakanan ana iya kera wasu abubuwan haɓaka a cikin dakin gwaje-gwaje. Ana iya amfani da waɗannan don tada samar da sababbin ƙwayoyin cuta a cikin marasa lafiya waɗanda ke buƙatar su.
Ana iya amfani da nau'ikan G-CSF daban-daban:
- Lenograstim (Granocyte®)
- Filgrastim (Neupogen®)
- Lipegfilgrastim (Lonquex®)
- Pegylated filgrastim (Neulasta®)
Wanene ke buƙatar abubuwan haɓaka?
Ko ana buƙatar jiyya tare da G-CSF ko a'a ya dogara da:
- Nau'i da mataki na lymphoma
- Chemotherapy
- Ko neutropenic sepsis ya faru a baya
- Magani na baya
- Shekaru
- Janar kiwon lafiya
Alamomi ga G-CSF
Akwai dalilai da yawa da ya sa marasa lafiya na lymphoma na iya buƙatar karɓar G-CSF. Dalilan na iya haɗawa da:
- Hana neutropenic sepsis. Chemotherapy don lymphoma yana nufin kashe ƙwayoyin lymphoma amma wasu ƙwayoyin lafiya kuma za su iya shafa. Wannan ya hada da fararen jini da ake kira neutrophils. Jiyya tare da G-CSF yana taimakawa ƙididdigar neutrophil don murmurewa da sauri. Ana iya amfani dashi don rage haɗarin neutropenic sepsis. Hakanan za su iya hana jinkiri ko raguwar kashi a cikin hawan chemotherapy.
- Magance sepsis neutropenic. Neutropenic sepsis shine lokacin da majiyyaci tare da ƙananan ƙananan neutrophils ya sami kamuwa da cuta wanda ba za su iya yin yaki ba kuma ya zama septic. Idan ba su sami magani na gaggawa ba, yana iya zama barazana ga rayuwa.
- Don haɓaka samar da ƙwayoyin sel da haɓakawa kafin a dasa kasusuwa. Abubuwan haɓaka suna ƙarfafa kasusuwan kasusuwa don yin ƙananan ƙwayoyin cuta a adadi mai yawa. Har ila yau, suna ƙarfafa su su fita daga cikin kasusuwa zuwa cikin jini, inda za a iya tattara su cikin sauƙi.
Ta yaya ake bayarwa?
- G-CSF yawanci ana ba da shi azaman allura a ƙarƙashin fata (a ƙarƙashin fata)
- Ana yin allurar farko a asibiti don lura da duk wani yanayi
- Ma'aikaciyar jinya na iya nuna wa majiyyaci ko mai goyan baya yadda ake yi wa G-CSF allura a gida.
- Wata ma'aikaciyar jinya ta al'umma na iya ziyartar kowace rana don yin allura, ko za a iya yin ta a aikin tiyatar GP.
- Yawancin lokaci suna zuwa cikin sirinji masu amfani guda ɗaya, waɗanda aka riga aka cika su
- Ya kamata a adana alluran G-CSF a cikin firiji.
- Cire allurar daga cikin firij mintuna 30 kafin a bukace ta. Ya fi jin daɗi idan zafin jiki ne.
- Ya kamata marasa lafiya su auna zafin jiki kowace rana kuma su kasance a faɗake don wasu alamun kamuwa da cuta.
Tasirin alluran G-CSF
Za a gwada matakan fararen ƙwayoyin jini a cikin jiki akai-akai tare da gwajin jini yayin da marasa lafiya ke yin alluran G-CSF.
Ƙarin illa na gama gari
- Tashin zuciya
- Vomiting
- Kuna ciwo
- Fever
- gajiya
- Asarar gashi
- Zawo ko maƙarƙashiya
- Dizziness
- Rash
- ciwon kai
lura: wasu marasa lafiya na iya fama da matsanancin ciwon kashi, musamman ma a cikin ƙananan baya. Wannan yana faruwa yayin da alluran G-CSF ke haifar da haɓaka da sauri a cikin neutrophils da amsa kumburi a cikin kasusuwa. Barrin kasusuwa yana cikin yankin ƙashin ƙugu (hip/ƙasashen baya). Wannan yana faruwa a lokacin da fararen jini ke dawowa. Ƙaramin mai haƙuri ya fi jin zafi, kamar yadda kasusuwan kasusuwa har yanzu yana da yawa lokacin da yake matashi. Babban majiyyaci yana da ƙarancin ƙashin ƙashi kuma sau da yawa ya rage zafi amma ba koyaushe ba. Abubuwan da za su iya taimakawa rage rashin jin daɗi:
- Paracetamol
- Kunshin zafi
- Loratadine: maganin antihistamine na kan gaba, wanda ke rage amsawar kumburi
- Tuntuɓi ƙungiyar likitocin don karɓar analgesia mai ƙarfi idan abin da ke sama bai taimaka ba
Bayar da rahoton duk wani mummunan illa ga ƙungiyar kula da lafiyar ku.
Rarer gefen-tasirin
Wasu marasa lafiya za su iya samun girma mai girma. Gayawa likita idan kuna da:
- Jin cikawa ko rashin jin daɗi a gefen hagu na ciki, kawai a ƙarƙashin haƙarƙarin
- Ciwo a gefen hagu na ciki
- Jin zafi a saman kafadar hagu
