Hoto mai sauri na lymphoma mai girma B-cell (DLBCL) a cikin yara
Wannan sashe taƙaitaccen bayani ne na yaɗuwar babban lymphoma cell B (DLBCL) a cikin yara masu shekaru 0-14. Don ƙarin bayani mai zurfi duba ƙarin sassan da ke ƙasa.
Menene?
Yaduwa babba B-cell lymphoma (DLBCL) wani m (mai girma da sauri) B-cell wanda ba Hodgkin lymphoma. Yana tasowa daga B lymphocytes (farin jini Kwayoyin) waɗanda suke girma ba tare da karewa ba. Waɗannan ƙananan ƙwayoyin ƙwayoyin cuta na B suna taruwa a cikin ƙwayoyin lymph da ƙwayoyin lymph, a cikin tsarin lymphatic, wanda ke cikin tsarin rigakafi. Saboda ana samun nama na lymph a ko'ina cikin jiki, DLBCL na iya farawa a kusan kowane bangare na jiki kuma ya yada zuwa kusan kowace gabo ko nama a cikin jiki.
Wanene ya shafa?
DLBCL yana da kusan kashi 15% na duk lymphoma da ke faruwa a cikin yara. DLBCL ya fi kowa a cikin yara maza fiye da a cikin 'yan mata. DLBCL shine mafi yawan nau'in lymphoma na yau da kullum a cikin manya, yana lissafin kusan kashi 30 cikin dari na lokuta na lymphoma na manya.
Jiyya da tsinkaya
DLBCL a cikin yara yana da kyakkyawan hangen nesa (hangen nesa). Kusan kashi 90% na yara suna warkewa bayan sun sami daidaitaccen chemotherapy da immunotherapy. Akwai bincike da yawa da ke shiga cikin magance wannan lymphoma, tare da mai da hankali kan binciken yadda za a rage tasirin da aka yi a baya, ko sakamako masu illa daga maganin mai guba wanda zai iya faruwa watanni zuwa shekaru bayan jiyya.
Bayanin babban ƙwayar lymphoma B-cell (DBCL) a cikin yara
Lymphomas rukuni ne na ciwon daji na tsarin lymphatic. Lymphoma yana faruwa ne lokacin da lymphocytes, waɗanda nau'in farin jini ne, suka sami maye gurbin DNA. Matsayin lymphocytes shine yaki da kamuwa da cuta, a matsayin wani ɓangare na jiki garkuwar jiki. akwai B-lymphocytes (B-cell) da T-lymphocytes (T-cells) waɗanda ke taka rawa daban-daban.
A cikin DLBCL ƙwayoyin lymphoma suna rarraba kuma suna girma ba tare da kulawa ba ko kuma ba sa mutuwa lokacin da ya kamata. Akwai manyan nau'ikan lymphoma guda biyu. Ana kiran su Lymphoma na Hodgkin (HL) da kuma lymphoma ba Hodgkin (NHL). An kuma raba Lymphomas zuwa:
- Indolent (jinkirin girma) lymphoma
- M (mai girma da sauri) lymphoma
- Kwayar B-cell su ne ƙananan ƙwayoyin lymphocytes B-cell kuma sun fi kowa. B-cell lymphomas suna da kusan kashi 85 cikin dari na dukkanin lymphomas
- T-cell lymphoma su ne marasa T-cell lymphocytes. T-cell lymphomas suna da kusan kashi 15% na dukkanin lymphomas
Yaduwa babba B-cell lymphoma (DLBCL) wani m (mai girma da sauri) B-cell wanda ba Hodgkin lymphoma. DLBCL yana da kusan kashi 15% na duk lymphomas da ke faruwa a cikin yara. DLBCL ita ce lymphoma mafi yawan gaske a cikin manya, wanda ke lissafin kusan kashi 30 cikin dari na dukkanin kwayoyin lymphoma a cikin manya.
DLBCL yana tasowa daga balagaggu B-cell daga ko dai cibiyar germinal na kumburin lymph, ko kuma daga ƙwayoyin B da aka sani da ƙwayoyin B masu kunnawa. Don haka, akwai nau'ikan DLBCL guda biyu da suka fi kowa:
- Cibiyar Germinal B-cell (GCB)
- Kunna B-cell (ABC)
Ba a san ainihin dalilin DLBCL a cikin yara ba. Yawancin lokaci babu wani bayani mai ma'ana game da inda ko yadda yaro ya kamu da ciwon daji kuma babu wata shaida da ke nuna iyaye da masu kulawa / masu kulawa zasu iya hana lymphoma daga tasowa, ko haifar da shi.
Wanene ke yaduwa da babban lymphoma B-cell (DLBCL) ya shafa?
Yaduwa babban lymphoma B-cell (DLBCL) na iya faruwa a cikin mutane na kowane zamani ko jinsi. An fi ganin DLBCL a cikin manyan yara da matasa (mutane masu shekaru 10 - 20). Yana faruwa akai-akai a cikin yara maza fiye da 'yan mata.
Ba a san dalilin DLBCL ba. Babu wani abu da kuka yi ko ba ku yi ba wanda ya jawo haka . Ba shi da cuta kuma ba za a iya yada shi ga wasu mutane ba.
Duk da yake dalilai masu yiwuwa na DLBCL ba a bayyane suke ba, akwai wasu abubuwan haɗari wanda ke da alaƙa da lymphoma. Ba duk mutanen da ke da waɗannan abubuwan haɗari ba ne za su ci gaba da haɓaka DLBCL. Abubuwan haɗari sun haɗa da (ko da yake haɗarin yana da ƙasa sosai):
- Cutar da ta gabata tare da cutar Epstein-Barr (EBV) - wannan ƙwayar cuta ita ce ta gama gari na zazzabin gland
- Raunan tsarin rigakafi saboda cututtukan da aka gada na rigakafi (cututtukan autoimmune kamar dyskeratosis congenita, lupus systemic, rheumatoid arthritis)
- HIV
- Maganin rigakafi wanda ake sha don hana ƙin yarda da shi bayan dashen gabbai
- Samun ɗan'uwa ko 'yar'uwa da ke da lymphoma (musamman tagwaye) an ba da shawarar samun alaƙar kwayoyin halittar iyali da ba kasafai ba (wannan yana da wuyar gaske kuma ba a ba da shawarar ga iyalai su yi gwajin kwayoyin halitta ba)
Samun yaron da aka gano tare da lymphoma na iya zama mai matukar damuwa da kwarewa, babu wani abu mai kyau ko kuskure. Yawancin lokaci yana da ban tsoro da ban tsoro, yana da mahimmanci don ba da damar kanku da dangin ku lokaci don aiwatarwa da baƙin ciki. Hakanan yana da mahimmanci kada ku ɗauki nauyin wannan ganewar asali da kanku, akwai ƙungiyoyin tallafi da yawa waɗanda ke nan don taimaka muku da dangin ku a wannan lokacin, danna nan don neman ƙarin bayani game da tallafi ga iyalai waɗanda ke da yaro ko matashi tare da lymphoma.
Nau'o'in yaɗa manyan ƙwayoyin lymphoma B-cell (DLBCL) a cikin yara
Ana iya rarraba manyan ƙwayoyin lymphoma na B-cell (DLBCL) zuwa nau'i-nau'i dangane da nau'in tantanin halitta B wanda ya girma daga (wanda ake kira "kwayoyin asali").
- Cibiyar Germinal B-cell lymphoma (GBC): Nau'in GCB ya fi kowa a cikin marasa lafiya na yara fiye da nau'in ABC. Matasa sun fi kamuwa da cutar nau'in GCB (80-95% a cikin shekaru 0-20) fiye da manya kuma yana da alaƙa da ingantaccen sakamako idan aka kwatanta da nau'in ABC.
- Kunna B-cell Lymphoma (ABC): Nau'in ABC ya fito ne daga wuraren bayan-germinal (na tantanin halitta) saboda ya fi girma B-cell malignancy. Ana kiransa nau'in ABC saboda an kunna ƙwayoyin B kuma suna aiki azaman masu ba da gudummawa na gaba ga martanin rigakafi.
Ana iya rarraba DLBCL azaman ko dai cibiyar B-cell (GCB) ko kunna B-cell (ABC). Masanin ilimin cututtuka da ke bincikar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta zai iya bambanta tsakanin waɗannan ta hanyar neman wasu sunadaran a kan kwayoyin lymphoma. A halin yanzu, ba a amfani da wannan bayanin don jagorantar jiyya. Koyaya, masana kimiyya suna gudanar da bincike don gano ko jiyya daban-daban suna da tasiri akan nau'ikan DLBCL daban-daban waɗanda ke tasowa daga sel daban-daban.
Alamun yaduwa babban lymphoma B-cell (DLBCL) a cikin yara
Alamun farko da yawancin mutane ke lura da su shine kullutu ko dunƙulewa da yawa waɗanda ba sa tafiya bayan makonni da yawa. Kuna iya jin dunƙule ɗaya ko fiye a wuyan yaronku, hammata, ko makwancinsa. Waɗannan kullun sun kumbura ƙwayoyin lymph, inda ƙananan lymphocytes ke girma. Wadannan kullukan sukan fara farawa a wani bangare na jikin yaro, yawanci kai, wuyansa ko kirji sannan sukan yaduwa ta hanyar da za a iya gani daga wani bangare na tsarin lymphatic zuwa na gaba. A cikin matakan ci gaba, cutar na iya yaduwa zuwa huhu, hanta, kasusuwa, bargon kashi ko wasu gabobin.
Akwai nau'in lymphoma da ba kasafai ba wanda ke gabatar da taro mai matsakaici, wanda aka sani da shi babban mediastinal babba B-cell lymphoma (PMBCL). An yi amfani da wannan lymphoma a matsayin wani nau'i na DLBCL amma an sake rarraba shi. PMC shi ne lokacin da lymphoma ya samo asali daga thymic B-cell. Thymus wata kwayar halitta ce ta lymphoid dake bayan kashin mahaifa (kirji).
Mafi yawan alamun bayyanar cututtuka na DLBCL sun haɗa da:
- Kumburi mara zafi na nodes na lymph a wuyansa, ƙarƙashin hannu, makwancin gwaiwa ko ƙirji
- Ƙunƙarar numfashi - saboda ƙananan ƙwayoyin lymph a cikin ƙirji ko matsakaicin matsakaici
- Tari (yawanci bushe tari)
- gajiya
- Wahalar murmurewa daga kamuwa da cuta
- Fata mai ƙaiƙayi (pruritus)
Alamomin B kalma ce da ke bayyana alamomi masu zuwa:
- gumi na dare (musamman da dare, inda zaku buƙaci canza kayan bacci da kayan bacci)
- Zazzaɓi mai tsayi
- Baceccen asarar rashin lafiya
Kusan kashi 20% na yara masu DLBCL suna tare da taro a cikin ƙirji na sama. Ana kiran wannan "matsalolin tsakiya". , Yawan yawa a cikin ƙirji na iya haifar da ƙarancin numfashi, tari ko kumburin kai da wuyansa saboda ciwon daji yana danna bututun iska ko manyan jijiya sama da zuciya.
Yana da mahimmanci a lura cewa yawancin waɗannan alamun suna da alaƙa da abubuwan da ke haifar da banda ciwon daji Wannan yana nufin lymphoma na iya zama da wahala ga likitoci su tantance.
Ganewar babban ƙwayar lymphoma B-cell (DLBCL)
A biopsy Ana buƙatar koyaushe don ganewar asali na lymphoma mai girma B-cell. A biopsy aiki ne don cire a lymph node ko wani nama maras al'ada don duba shi a ƙarƙashin microscope ta likitan ilimin cututtuka. Yawanci ana yin kwayar halitta a ƙarƙashin maganin sa barci na gabaɗaya don yara don taimakawa rage damuwa.
Gabaɗaya, ko dai ainihin biopsy ko ƙwayar node biopsy shine mafi kyawun zaɓi na bincike. Wannan don tabbatar da likitoci sun tattara isasshen adadin nama don kammala gwajin da ya dace don ganewar asali.
Ana jiran sakamako na iya zama lokaci mai wahala. Yana iya taimakawa wajen yin magana da danginku, abokai ko ƙwararren ma'aikacin jinya.
Tsarin lymphoma mai girma B-cell (DLBCL)
Da zarar a ganewar asali na DLBCL an yi, ana buƙatar ƙarin gwaje-gwaje don ganin inda kuma a cikin jiki akwai lymphoma. Ana kiran wannan shirya. The shirya na lymphoma yana taimaka wa likita don sanin mafi kyawun magani ga yaro.
Akwai matakai 4, daga mataki na 1 (lymphoma a yanki ɗaya) zuwa mataki na 4 (lymphoma wanda ya yadu ko ci gaba).
- Matakin farko yana nufin mataki na 1 da wasu matakai na 2 lymphomas. Ana iya kiran wannan kuma 'yanayin gida'. Mataki na 1 ko 2 yana nufin cewa ana samun lymphoma a wuri ɗaya ko wasu yankuna kusa da juna.
- Mataki na gaba yana nufin lymphoma mataki na 3 da mataki na 4, kuma lymphoma ce mai yaduwa. A mafi yawan lokuta, lymphoma ya yadu zuwa sassan jikin da ke nesa da juna.
'Babban' matakin lymphoma yayi sauti game da, amma lymphoma shine abin da aka sani da kansar tsarin. Yana iya yaduwa cikin tsarin lymphatic da nama kusa. Wannan shine dalilin da ya sa ake buƙatar magani na tsarin (chemotherapy) don magance DLBCL.
Abubuwan da ake buƙata na iya haɗawa da:
- Yin gwajin jini (kamar: cikakken adadin jini, sunadarai na jini da erythrocyte sedimentation rate (ESR) don neman shaidar kumburi)
- Chef x-ray - waɗannan hotuna za su taimaka wajen gano kasancewar cututtuka a cikin kirji
- Positron emission tomography (PET) duba - yi don fahimtar duk wuraren cututtuka a cikin jiki kafin fara magani
- Utedididdigar zanan Tomography (CT)
- Bone marrow biopsy (yawanci ana yin shi idan shaidar ci gaba da cutar)
- Lumbar dam - Idan ana zargin lymphoma a cikin kwakwalwa ko kashin baya
Yaron ku kuma yana iya sha da yawa gwajin asali kafin fara wani magani. Wannan don duba aikin gabobin ne. Ana iya maimaita waɗannan lokacin da bayan jiyya don tantance ko maganin ya shafi aikin gabobin jiki. Gwaje-gwajen da ake buƙata na iya haɗawa da; ;
- Nazarin jiki
- Muhimman abubuwan lura (Matsalolin jini, zafin jiki, da ƙimar bugun jini)
- Duban zuciya
- Duban koda
- Gwajin numfashi
- Yin gwajin jini
Yawancin waɗannan shirya da kuma gwajin aikin gabobi Ana sake yin su bayan jiyya don bincika ko maganin lymphoma ya yi aiki da kuma lura da tasirin maganin ya yi a jiki.
Hasashen manyan ƙwayoyin lymphoma B-cell (DLBCL)
DLBCL a cikin yara yana da kyakkyawan hangen nesa (hangen nesa). Kusan kashi 9 cikin 10 (90%) na yara suna warkewa bayan sun karɓi daidaitattun chemotherapy da kuma immunotherapy. Akwai bincike da yawa da ke neman yin maganin wannan lymphoma, tare da mai da hankali kan bincikar yadda za a rage sakamako mai lalacewa, ko sakamako masu illa daga maganin mai guba wanda zai iya faruwa watanni zuwa shekaru bayan jiyya.
Rayuwa na dogon lokaci da zaɓuɓɓukan magani sun dogara da abubuwa da yawa, gami da:
- Shekarun yaron ku a ganewar asali
- Yawan ko matakin ciwon daji
- Bayyanar ƙwayoyin lymphoma a ƙarƙashin microscope (siffa, aiki da tsarin sel)
- yadda lymphoma ke amsa magani
Jiyya na lymphoma mai girma B-cell
Da zarar an kammala duk sakamakon binciken kwayoyin halitta da na binciken, likita zai duba waɗannan don yanke shawarar mafi kyawun magani ga ɗanka. A wasu cibiyoyin ciwon daji, likita zai sadu da ƙungiyar kwararru don tattauna mafi kyawun zaɓin magani. Ana kiran wannan a Ƙungiyar multidisciplinary (MDT) haduwa.
Likitocin za su yi la'akari da abubuwa da yawa game da lymphoma na ɗanku da lafiyar gabaɗaya don yanke shawara lokacin da kuma wane magani ake buƙata. Wannan ya dogara ne akan;
- Matsayi da darajar lymphoma
- Alamun
- Shekaru, tarihin likita na baya & lafiyar gabaɗaya
- Lafiyar jiki da tunani na yanzu
- Yanayin zamantakewa
- Abubuwan da ake so na iyali
Tun da DLBCL lymphoma ne mai girma da sauri, yana buƙatar a yi masa magani da sauri - sau da yawa a cikin kwanaki zuwa makonni na ganewar asali. Maganin DLBCL ya haɗa da haɗuwa da chemotherapy da kuma immunotherapy
Ana iya bi da wasu marasa lafiya na DLBCL matasa tare da babban tsarin chemotherapy da ake kira R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, da kuma prednisolone). Wannan yawanci zai dogara ne akan ko ana jinyar ɗanku a cikin asibitin yara ko kuma babban asibitin manya.
Daidaitaccen magani na yara don matakin farko na DLBCL (matakin I-IIA):
- BFM-90/95: 2 - 4 hawan keke na chemotherapy dangane da matakin cuta
- Magungunan miyagun ƙwayoyi sun haɗa da: cyclophosphamide, cytarabine, methotrexate, mercaptopurine, vincristine, pegaspargase, prednisolone, pirarubicin, dexamethasone.
- COG-C5961: 2 - 4 hawan keke na chemotherapy dangane da matakin cuta
Daidaitaccen magani na yara don babban mataki DLBCL (mataki IIB-IVB):
- Saukewa: COG-C5961: 4 - 8 hawan keke na chemotherapy dangane da matakin cuta
- Magungunan miyagun ƙwayoyi sun haɗa da: cyclophosphamide, cytarabine, doxorubicin hydrochloride, etoposide, methotrexate, prednisolone, vincristine.
- BFM-90/95: 4 - 6 hawan keke na chemotherapy dangane da matakin cuta
- Magungunan miyagun ƙwayoyi sun haɗa da: cyclophosphamide, cytarabine, methotrexate, mercaptopurine, vincristine, pegaspargase, prednisolone, pirarubicin, dexamethasone.
Sakamakon gama gari na magani
Maganin DLBCL ya zo tare da haɗarin haɓaka tasirin sakamako daban-daban. Kowane tsarin kulawa yana da illa na mutum ɗaya kuma likitan ku da/ko ƙwararrun ma'aikacin jinya za su bayyana muku waɗannan abubuwan gare ku da ɗan ku kafin fara jiyya.
Wasu daga cikin abubuwan da suka fi dacewa na jiyya don yaduwa babban lymphoma B-cell sun hada da:
- Anemia (ƙananan ƙwayoyin jini)
- Thrombocytopenia (ƙananan platelets)
- Neutropenia (ƙananan farin jini)
- Nuna da zubar
- Matsalolin hanji kamar maƙarƙashiya da gudawa
- gajiya
- Rage haihuwa
Ƙungiyar likitan ku, likita, ma'aikacin jinya ko likitan magunguna, ya kamata su ba ku bayani game da naku magani, da na kowa illa, menene alamun da za a ba da rahoto da wanda za a tuntuɓar. Idan ba haka ba, don Allah a yi waɗannan tambayoyin.
Kiyaye haihuwa
Wasu jiyya na lymphoma na iya rage haihuwa. Wannan yana yiwuwa tare da wasu ƙa'idodin chemotherapy (haɗuwar magunguna) da babban adadin chemotherapy da aka yi amfani da su kafin dashen kwayar halitta. Radiotherapy zuwa ƙashin ƙugu kuma yana ƙara yuwuwar rage yawan haihuwa. Wasu magungunan antibody kuma na iya shafar haihuwa, amma wannan bai fito fili ba.
Ya kamata likitan ku ba da shawara kan ko za a iya shafar haihuwa Yi magana da likita da/ko ƙwararrun ma'aikacin jinya kafin a fara jiyya game da ko za a shafa haihuwa.
Don ƙarin bayani ko shawara game da DLBCL na yara, jiyya, sakamako masu illa, tallafi da ake samu ko yadda za a kewaya tsarin asibiti, tuntuɓi layin tallafi na kula da lymphoma a kan 1800 953 081 ko email mu a nurse@lymphoma.org.au
Kulawa mai biyo baya
Da zarar an gama jiyya, za a yi wa yaranku gwajin gwaji. Waɗannan binciken ne don duba yadda maganin ya yi aiki. Binciken zai nuna wa likitoci yadda lymphoma ya amsa magani. Ana kiran wannan amsa ga jiyya kuma ana iya siffanta shi da:
- Cikakken amsa (CR ko babu alamun lymphoma da suka rage) ko a
- Amsa juzu'i (PR ko har yanzu akwai lymphoma, amma ya rage girman)
Yaron ku zai buƙaci likitan su ya bi shi tare da alƙawura na yau da kullun, yawanci kowane watanni 3-6. Waɗannan alƙawura suna da mahimmanci don ƙungiyar likitocin su duba yadda suke murmurewa daga jiyya. Waɗannan alƙawura suna ba ku dama mai kyau don yin magana da likita ko ma'aikacin jinya game da duk wata damuwa da kuke da ita. Tawagar likitocin za su so sanin yadda yaranku da ku ke ji a zahiri da tunani, da kuma:
- Yi nazarin tasirin maganin
- Kula da duk wani sakamako mai gudana daga maganin
- Kula da duk wani sakamako na marigayi daga jiyya a kan lokaci
- Kula da alamun sake dawowar lymphoma
Wataƙila yaronku zai yi gwajin jiki da gwajin jini a kowane alƙawari. Baya ga nan da nan bayan magani don sake duba yadda maganin ya yi aiki, ba a yawanci yin scanning sai dai idan akwai wani dalili na musamman. Idan yaronka yana da lafiya, alƙawura na iya zama raguwa akai-akai akan lokaci.
Maimaitawa ko gudanarwa na DLBCL
Maimaituwa lymphoma shine lokacin da ciwon daji ya dawo, refractory lymphoma shine lokacin da ciwon daji ba ya amsawa jiyya na farko. Ga wasu yara da matasa, DLBCL ya dawo kuma a wasu lokuta da ba kasafai ba ya amsa ga jiyya ta farko (mai hana). Ga waɗannan marasa lafiya akwai wasu jiyya waɗanda za su iya yin nasara, waɗannan sun haɗa da:
- Haɗaɗɗen ƙwayar cuta mai girma bi da autologous kara cell dashi ko wani allogeneic stem cell dashi (bai dace da kowa ba)
- Haɗuwa chemotherapy
- immunotherapy
- Radiotherapy
- Shiga gwaji na asibiti
Lokacin da ake zargin mutum ya sake kamuwa da cutar, sau da yawa ana yin irin wannan jarrabawar, wanda ya haɗa da gwaje-gwajen da aka bayyana a sama a cikin binciken. ganewar asali da kuma shirya sashe.
Jiyya a karkashin bincike
Akwai jiyya da yawa waɗanda a halin yanzu ana gwada su a cikin gwaje-gwajen asibiti a duniya don marasa lafiya tare da sabbin cututtukan da aka gano da kuma sake dawowa. Wasu daga cikin waɗannan jiyya sun haɗa da:
- Gwaje-gwaje da yawa suna nazarin rage bayanin mai guba da sakamakon ƙarshen jiyya na chemotherapy
- CAR T-cell far
- Copanlisib (ALIQOPATM - PI3K mai hanawa)
- Venetoclax (VENCLEXTATM - Mai hana BCL2)
- Temsirolimus (TORISOLTM)
- CUDC-907 (labari da aka yi niyya far)
Me ke faruwa bayan jiyya?
Late effects
Wani lokaci sakamako na gefe daga jiyya na iya ci gaba ko haɓaka watanni ko shekaru bayan an gama jiyya. Ana kiran wannan sakamako na ƙarshe. Don ƙarin bayani, jeka sashin 'lalata sakamako' don ƙarin koyo game da wasu daga cikin abubuwan farko da na ƙarshen waɗanda zasu iya faruwa daga jiyya na lymphoma.
Yara da matasa na iya samun illa masu alaƙa da jiyya waɗanda zasu iya bayyana watanni ko shekaru bayan jiyya, gami da matsalolin haɓakar ƙashi da haɓaka gabobin jima'i a cikin maza, rashin haihuwa, da cututtukan thyroid, cututtukan zuciya da huhu. Yawancin tsarin kulawa na yanzu da binciken bincike yanzu suna mayar da hankali kan ƙoƙarin rage haɗarin waɗannan sakamako na ƙarshe.
Don waɗannan dalilai yana da mahimmanci waɗanda suka tsira daga yaɗuwar manyan ƙwayoyin lymphoma B-cell (DLBCL) suna samun bi-bi-da-bi da sa ido akai-akai.
